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Monoclonal antibodies to intra-acrosomal proteins inhibit gamete binding
- 1.0191232 - UMG-J 20010303 RIV US eng J - Journal Article
Pěknicová, Jana - Čapková, Jana - Geussová, Gizela - Ivanova, M. - Mollova, M.
Monoclonal antibodies to intra-acrosomal proteins inhibit gamete binding.
Theriogenelogy. Roč. 56, č. 2 (2001), s. 211-223. ISSN 0093-691X. E-ISSN 1879-3231
R&D Projects: GA ČR GV524/96/K162; GA ČR GA303/00/1651; GA MZd NJ5851
Keywords : secondary sperm-zona pellucida binding * intraacrosomal proteins * acrosin
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 1.965, year: 2001
The sperm-zona pellucida-binding assay in vitro was used as a functional test for zona pellucida-binding ability of boar spermatozoa after co-incubation with monoclonal antibodies against intra-acrosomal proteins to reduce the secondary sperm-zona pellucida-binding with statistically significant difference. This suggests the role of these proteins in the early phases of fertilization.
Permanent Link: http://hdl.handle.net/11104/0086988
Number of the records: 1