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Inhibition of the antibody responses to rat blood transfusion antigens in mice by boar seminal immunosuppressive fraction
- 1.0191169 - UMG-J 20010238 RIV DK eng J - Journal Article
Veselský, Leopold - Jonáková, Věra - Dostál, Jaromír - Holáň, Vladimír - Voburka, Zdeněk - Drahorád, Josef - Maňásková, Pavla - Železná, Blanka
Inhibition of the antibody responses to rat blood transfusion antigens in mice by boar seminal immunosuppressive fraction.
American Journal of Reproductive Immunology and Microbiology. Roč. 44, č. 6 (2000), s. 325-335. ISSN 8755-8920
R&D Projects: GA ČR GA204/98/0827; GA ČR GV524/96/K162; GA ČR GA303/99/0357; GA MZd NC4534
Institutional research plan: CEZ:AV0Z5052915
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 1.932, year: 2000
ISF and H- fraction were proved to be equal complexes of porcine seminal plasma (PSP) proteins PSP I and PSP II. Both inhibited antibody responses to rat erythrocytes and serum and the concentrations of IgM, IgG, IgG1 and IgG2 after the first transfusion with a long-lasting effect. Both suppressed the secondary antibody production if applied before the second transfusion. IgA and IgG3 stayed uninfluenced. ISF and H- fraction had an equal immunosuppressive effect. ISF was determined to be powerful in overcoming unwanted antibody responses to xenotransfusion
Permanent Link: http://hdl.handle.net/11104/0086926
Number of the records: 1