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Mannosides as crucial part of bioactive supports for cultivation of human epidermal keratinocytes without feeder cells

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    SYSNO ASEP0189059
    Document TypeJ - Journal Article
    R&D Document TypeJournal Article
    Subsidiary JOstatní články
    TitleMannosides as crucial part of bioactive supports for cultivation of human epidermal keratinocytes without feeder cells
    Author(s) Labský, Jiří (UMCH-V)
    Dvořánková, B. (CZ)
    Smetana, Karel (UMCH-V)
    Holíková, Z. (CZ)
    Brož, L. (CZ)
    Gabius, H.J. (CZ)
    Source TitleBiomaterials. - : Elsevier - ISSN 0142-9612
    Roč. 24, č. 5 (2003), s. 863-872
    Number of pages10 s.
    Languageeng - English
    CountryNL - Netherlands
    Keywordscell therapy ; keratinocyte ; mannose
    Subject RIVCD - Macromolecular Chemistry
    R&D ProjectsGA203/00/1310 GA ČR - Czech Science Foundation (CSF)
    LN00A065 GA MŠMT - Ministry of Education, Youth and Sports (MEYS)
    ND6340 GA MZd - Ministry of Health (MZ)
    CEZAV0Z4050913 - UMCH-V
    AnnotationLarge-scale production of keratinocytes by cell culture is of interest for medical applications. Long-term cultivation of epidermal cells is presently possible with feeder cells, i.e. 3T3 fibroblasts with arrested mitosis, or with specially formulated culture medium. To define refinements for in vitro conditions, the analysis of the natural environment with growth-maintaining/stimulating factors can provide important clues. Cells with proliferative activity are located in the basal layer of the epidermis in close contact with a basement membrane.
    WorkplaceInstitute of Macromolecular Chemistry
    ContactEva Čechová, cechova@imc.cas.cz ; Tel.: 296 809 358
    Year of Publishing2004

Number of the records: 1  

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