0185190 - UJF-V 20000364 RIV GB eng J - Journal Article
Orlova, A. - Lebeda, Ondřej - Tolmachev, V. - Sjöberg, S. - Carlsson, J. - Lundquist, H.
Closo-dodecaborate(2-)anion as a prosthetic group for attachment of astatine to proteins. Aspects of the labelling chemistry with Chloramine-T.
Journal of Labelled Compounds and Radiopharmaceuticals. Roč. 43, - (2000), s. 251-260. ISSN 0362-4803. E-ISSN 1099-1344
Institutional research plan: CEZ:AV0Z1048901
Subject RIV: BG - Nuclear, Atomic and Molecular Physics, Colliders
Impact factor: 0.756, year: 2000

Closo-dodecaborate (2-) was proposed as a prosthetic groupfor direct labelling of proteins with .sup.211 At for radionuclide therapy. Astatination of closo-dodecaborate (2-) anion using Chloramine-T was studied, and the influence ofpH, reaction time, amount of substrate and oxidant was determined. A maximum labelling yield of 55-75
Permanent Link: http://hdl.handle.net/11104/0081601