Number of the records: 1
Selected Ion Flow Tube Studies of the Reactions of H3O+, NO+ and O2+ with the Anaesthetic Gases Halothane, Isoflurane and Sevoflurane
- 1.0181487 - UFCH-W 20020157 RIV GB eng J - Journal Article
Wang, T. - Smith, D. - Španěl, Patrik
Selected Ion Flow Tube Studies of the Reactions of H3O+, NO+ and O2+ with the Anaesthetic Gases Halothane, Isoflurane and Sevoflurane.
Rapid Communications in Mass Spectrometry. Roč. 16, - (2002), s. 1860-1870. ISSN 0951-4198. E-ISSN 1097-0231
R&D Projects: GA ČR GA203/00/0632; GA ČR GA203/02/0737
Institutional research plan: CEZ:AV0Z4040901
Keywords : ion-molecule reactions * SIFT * anaesthetics
Subject RIV: CF - Physical ; Theoretical Chemistry
Impact factor: 2.372, year: 2002
We have carried out a study of the reactions of H3O+, NO+ and O2+, the commonly used precursor ions for SIFT-MS, with three anaesthetic gases, halothane, isoflurane and sevoflurane. The motivation for this study was to provide the necessary kinetic data that would allow the quantification of these anaesthetic gases in operating theatre air and in the breath of theatre staff and post-operative patients. A clear negative result from these experiments is that NO+, although undergoing the simplest chemistry is unsuitable for this SIFT-MS application. However, although the ion chemistry of the H3O+ and O2+ with these compounds is very complex, there being several product ions in each reaction, many of which react rapidly with water molecules, monitor ionns have been identified for all three anaesthetic gases when using H3O+ and O2+ as precursor ions. The detailed ion chemistry is discussed and the specific monitor ions are indicated.
Permanent Link: http://hdl.handle.net/11104/0001894
Number of the records: 1