0173768 - UEM-P 20033092 RIV GB eng M - Monography Chapter
Rössner ml., Pavel - Binková, Blanka - Chvátalová, Irena - Šrám, Radim
The effect of acrylonitrile exposure on the expression of p53 and p21WAF1 proteins in the blood plasma of occupationally exposed workers and in human diploid lung fibroblasts.
Human Monitoring for Genetic Effects. Amsterdam: IOS Press, 2003 - (Cebulska-Wasilewska, A.; Au, W.; Šrám, R.), s. 262. NATO Sci. Series I., 351
R&D Projects: GA MŠMT OK 390; GA ČR GP310/01/P030
Grant - others:EC(XE) IC 15-CT97-0302
Institutional research plan: CEZ:AV0Z5039906
Keywords : acrylonitrile * occupational exposure * p53 protein
Subject RIV: EB - Genetics ; Molecular Biology

The effect of exposure to acrylonitrile (ACN) on the expression of p53 and p21WAF1 proteins in blood serum of acrylonitrile-exposed workers from petrochemical industry was evaluated. The expression of both proteins was determined by ELISA immunoassay and western blotting. ACN induced also the expression of heat shock proteins hsp32 and hsp70 which may be sensitive biomarkers of environmental pollution.
Permanent Link: http://hdl.handle.net/11104/0070794