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Assessment of biotransformation of the arene moiety of styrene in volunteers and occupationally oxposed workers

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    0173699 - UEM-P 20033016 RIV US eng J - Journal Article
    Manini, P. - Buzio, L. - Andeoli, R. - Goldoni, M. - Bergamaschi, E. - Jakubowski, M. - Vodička, Pavel - Hirvonen, A. - Mutti, A.
    Assessment of biotransformation of the arene moiety of styrene in volunteers and occupationally oxposed workers.
    Toxicology and Applied Pharmacology. Roč. 189, - (2003), s. 160-169. ISSN 0041-008X. E-ISSN 1096-0333
    Grant - others:QLK4-CT(IT) 1999-01368
    Institutional research plan: CEZ:AV0Z5039906
    Keywords : styrene exposure
    Subject RIV: FM - Hygiene
    Impact factor: 2.851, year: 2003

    Styrene is a chemical widely used in the plastic industry. Zhe main pathway of styrene metabolism in humans occurs via the oxidation to styrene-7,8-oxide (7,8-SO). The aim of this study was the investigation of a minor metabolic route, involving the oxidation of the arene moiety of styrene, by means of the characterization of the conjugated urinary metabolites of 4-vinylphenol (4-VP).
    Permanent Link: http://hdl.handle.net/11104/0070725


     
     

Number of the records: 1  

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