0173687 - UEM-P 20033003 RIV NL eng J - Journal Article
Zídek, Zdeněk - Potměšil, Petr - Kmoníčková, Eva - Holý, Antonín
Immunobiological activity of N-[2-(phosphonomethoxy)-alkyl] derivatives of N6-substituted adenines, and 2,6-diaminopurines.
European Journal of Pharmacology. Roč. 475, - (2003), s. 149-159. ISSN 0014-2999. E-ISSN 1879-0712
R&D Projects: GA ČR GA305/00/0048
Institutional research plan: CEZ:AV0Z5039906; CEZ:AV0Z4055905
Keywords : acyclic nucleoside phosphonates
Subject RIV: FR - Pharmacology ; Medidal Chemistry
Impact factor: 2.352, year: 2003

Several newly developed acyclic nucleoside phosphonates have been found to activate immunocompetent cells for secretion of cytokines and chemokines implicated in regulation of virus replication. These compounds might be prospective candidates for antiviral therapeutic exploitation.
Permanent Link: http://hdl.handle.net/11104/0070714