0173573 - UEM-P 20023018 RIV NL eng J - Journal Article
Binková, Blanka - Šmerhovský, Zdeněk - Strejc, P. - Boubelík, O. - Stávková, Zdena - Chvátalová, Irena - Šrám, Radim
DNA adducts and atherosclerotic: A study of accidental and sudden death males in the Czech Republic.
Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. č. 501 (2002), s. 115-128. ISSN 0027-5107. E-ISSN 1873-135X
R&D Projects: GA MŽP SI/340/1/97
Institutional research plan: CEZ:AV0Z5039906
Keywords : atherosclerosis * DNA-adducts * GSTM1 and CYP1A1 polymorphism
Subject RIV: DN - Health Impact of the Environment Quality
Impact factor: 3.158, year: 2002

The study tested the hypothesis that 'bulky' aromatic DNA adducts in smooth muscle cells of thoracic aortas taken at autopsy from sudden and accidental death male subjects are associated with the stage of atherosclerosis. The effect of known atherosclerotic risk factors such as age, smoking, plasma lipid and vitamin levels and somegenetic susceptibility markers were also evaluated.
Permanent Link: http://hdl.handle.net/11104/0070604