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Lihgt irradiation increases embryotoxicity of photodynamic therapy sensitizers (5-aminolevulinic acid and protoporphyrin IX) in chick ebryos
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SYSNO ASEP 0173425 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Ostatní články Title Lihgt irradiation increases embryotoxicity of photodynamic therapy sensitizers (5-aminolevulinic acid and protoporphyrin IX) in chick ebryos Author(s) Peterka, Miroslav (UEM-P) RID
Klepáček, I. (CZ)Source Title Reproductive Toxicology. - : Elsevier - ISSN 0890-6238
Roč. 15, - (2001), s. 111-116Number of pages 6 s. Language eng - English Country US - United States Keywords embryotoxicity Subject RIV EA - Cell Biology CEZ AV0Z5039906 - UEM-P MSM 111100005 Annotation We compared experimentally the photodynamic effect (light-toxic) and the side effect (dark-toxic) of the clinically attractive photosensitizers 5-aminolevulinic acid (ALA) and protoporphyrin IX (PP IX). Light irradiation of embryos following injection induced strong embryotoxic effects of both substances even at dark- ineffective doses. Workplace Institute of Experimental Medicine Contact Arzuv Čaryjeva, arzuv.caryjeva@iem.cas.cz, Tel.: 241 062 218, 296 442 218 Year of Publishing 2002
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