0173425 - UEM-P 20010021 RIV US eng J - Journal Article
Peterka, Miroslav - Klepáček, I.
Lihgt irradiation increases embryotoxicity of photodynamic therapy sensitizers (5-aminolevulinic acid and protoporphyrin IX) in chick ebryos.
Reproductive Toxicology. Roč. 15, - (2001), s. 111-116. ISSN 0890-6238. E-ISSN 1873-1708
Institutional research plan: CEZ:AV0Z5039906; CEZ:MSM 111100005
Keywords : embryotoxicity
Subject RIV: EA - Cell Biology
Impact factor: 1.697, year: 2001

We compared experimentally the photodynamic effect (light-toxic) and the side effect (dark-toxic) of the clinically attractive photosensitizers 5-aminolevulinic acid (ALA) and protoporphyrin IX (PP IX). Light irradiation of embryos following injection induced strong embryotoxic effects of both substances even at dark- ineffective doses.
Permanent Link: http://hdl.handle.net/11104/0070458