Spliceosomal Assembly on Precursor mRNA takes place in the nuclear speckles
1.
SYSNO ASEP
0173383
Document Type
C - Proceedings Paper (int. conf.)
R&D Document Type
Conference Paper
Title
Spliceosomal Assembly on Precursor mRNA takes place in the nuclear speckles
Author(s)
Raška, Ivan (UEM-P) Melčák, Ivo (UEM-P) Cermanová, Štěpánka (UEM-P)
Source Title
ELSO 2000. - Ženeva : Urban&Fischer, 2000
Pages
s. 26
Number of pages
1 s.
Action
ELSO 2000
Event date
02.09.2000-06.09.2000
VEvent location
Ženeva
Country
CH - Switzerland
Language
eng - English
Country
US - United States
Subject RIV
EB - Genetics ; Molecular Biology
R&D Projects
VS96129 GA MŠMT - Ministry of Education, Youth and Sports (MEYS)
GA304/00/1481 GA ČR - Czech Science Foundation (CSF)
GA302/99/0587 GA ČR - Czech Science Foundation (CSF)
CEZ
AV0Z5039906 - UEM-P
Annotation
Nucllear speckles (speckles), enriched in splicing factors, form a distinct nuclear compartment within the interchromatin space. It has been shown to serve vicinal active genes as a reservoir of splicing factors.We show that (pre-) spliceosomal assembbly on pre - mRNA is associated with the speckles in HeLa cells.
