Cell Physiology and Interactions of Biomaterials and Matrices

Number of the records: 1

SYSNO ASEP	0172322
Document Type	J - Journal Article
R&D Document Type	Journal Article
Subsidiary J	Ostatní články
Title	Cell Physiology and Interactions of Biomaterials and Matrices
Author(s)	Hunkeler, D. (CH) Vaňková, Radomíra (UEB-Q)_{RID, ORCID}
Source Title	Polymer News - ISSN 0032-3918 Roč. 28, č. 6 (2003), s. 193-197
Number of pages	5 s.
Language	eng - English
Country	DE - Germany
Keywords	Biomaterials ; Cell physiology ; Encapsulation
Subject RIV	CE - Biochemistry
R&D Projects	OC 840.20 GA MŠMT - Ministry of Education, Youth and Sports (MEYS)
CEZ	AV0Z5038910 - UEB-Q
Annotation	The effect of compression on Lactobacillus acidophilus was discussed. Their process includes the growth of bacteria, formulation, freeze drying, and compression to "encapsulate" cells. Cell viability remains above 90% with compression pressures of 60 MPa, though decreases strongly after application of 90 MPa. Cell viability has been lower for thicker coatings due to a higher resistance to rehydration. Overall, the total release time has varied from 5 to 9 hours, implying that this system could avoid cell release in the stomach and small intestines. Therefore, targeted cell delivery to the low intestines seems possible.
Workplace	Institute of Experimental Botany
Contact	David Klier, knihovna@ueb.cas.cz, Tel.: 220 390 469
Year of Publishing	2004

Number of the records: 1