0170654 - UEK-B 20020020 RIV GB eng J - Journal Article
Šafaříková, Miroslava - Šafařík, Ivo
Interaction of tricyclic drugs with copper phthalocyanine dye immobilized on magnetic carriers.
European Cells and Materials. 3(Suppl.2), - (2002), s. 188-191. ISSN 1473-2262. E-ISSN 1473-2262.
[International Conference on the Scientific and Clinical Applications of Magnetic Carriers /4./. Tallahassee, 09.05.2002-11.05.2002]
R&D Projects: GA MŠMT OC 523.80; GA AV ČR IBS6087204
Institutional research plan: CEZ:AV0Z6087904
Keywords : magnetic * tricyclic drugs * phthalocyanine
Subject RIV: CE - Biochemistry

Reactive copper phthalocyanine dye immobilized on silanized magnetite particles was used as a specific magnetic adsorbent for the study of interactions with several tricyclic drugs. Magnetically modified copper phthalocyanine specifically interacts with all tricyclic drugs tested (Amitriptyline, Diethazine, Chlorprothixene, Bisulepin, Prochlorperazine, Dothiepin, Thioridazine). This magnetic adsorbent can be used to isolate the target drugs from various samples using magnetic solid-phase extraction.
Permanent Link: http://hdl.handle.net/11104/0067737