Structure-Sweetness Relationships of Aspartame Derivatives by GUHA

0163403 - UACH-T 20023101 RIV DE eng C - Conference Paper (international conference)
Hálová, Jaroslava - Žák, Přemysl - Stopka, Pavel - Yuzuri, T. - Abe, Y. - Sakakibara, K. - Suezawa, H. - Hirota, M.
Structure-Sweetness Relationships of Aspartame Derivatives by GUHA.
Discovery Science. Lübeck: Springer, 2002, s. 291-296. ISBN 3-540-00188-3.
[International Conference, DS 2002 /5./. Lübeck (DE), 24.11.2002-26.11.2002]
Institutional research plan: CEZ:AV0Z4032918
Keywords : GUHA method
Subject RIV: CA - Inorganic Chemistry

Structure-Sweetness Relationships of Aspartame derivates have been established using fingerprintdescriptors by GUHA method. Guha is the acronym for General Unary Hypoteses Automaton.The glucophoric hypoteses on the reasons for sweetness of aspartame derivatives were generated. Moreover, new results on sweetness receptor site topology have been found. the results were confirmed both by theoretical studies of other authors and chemical evidence.
Permanent Link: http://hdl.handle.net/11104/0060645