0157585 - PAU-O 20023060 RIV US eng J - Journal Article
Simpson, A. G. B. - Lukeš, Julius - Roger, A. J.
The evolutionary history of kinetoplastids and their kinetoplasts.
Molecular Biology and Evolution. Roč. 19, č. 12 (2002), s. 2071-2083. ISSN 0737-4038. E-ISSN 1537-1719
R&D Projects: GA ČR GA204/00/1212
Institutional research plan: CEZ:AV0Z6022909
Keywords : Kinetoplastida * kinetoplast * evolution
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 5.271, year: 2002

Despite extensive phylogenetic analysis of small subunit ribosomal RNA (SSUrRNA) genes, the deep-level relationships among kinetoplastids remain poorly understood, limiting our grasp of their evolutionary history, especially the origins of their bizarre mitochondrial genome organizations. In this study we examine the SSUrRNA data in the light of a new markerÚcytoplasmic heat shock protein 90 (hsp90) sequences. Our phylogenetic analyses divide kinetoplastids into four main clades. Clades 1ů3 include the various bodonid kinetoplastids. Trypanosomatids comprise the fourth clade. SSUrRNA analyses give vastly different and poorly supported positions for the root of the kinetoplastid tree, depending on the out-group and analysis method.
Permanent Link: http://hdl.handle.net/11104/0055023