0142525 - FGU-C 20030012 RIV CH eng J - Journal Article
Villena, J. A. - Carmona, M. C. - Rodriguez de la Concepción, M. - Rossmeisl, Martin - Vinas, O. - Mampel, T. - Iglesias, R. - Giralt, M. - Villarroya, F.
Mitochondrial biogenesis in brown adipose tissue is associated with differential expression of transcription regulatory factors.
Cellular and Molecular Life Sciences. Roč. 59, č. 11 (2002), s. 1934-1944. ISSN 1420-682X. E-ISSN 1420-9071
Grant - others:Ministerio de Ciencia y Tecnología(ES) PM98.0188
Institutional research plan: CEZ:AV0Z5011922
Keywords : brown adipose tissue * mitochondria * transcription factors
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 5.259, year: 2002

The differentiation of brown adipocytes is associated with increased mitochondrial biogenesis and expression of components of respiratory chain/oxidative phosphorylation system. This study analyzes the expression of key regulatory molecules of this process, namely NRF-1 and ů2, Sp1 and PGC-1, during late fetal development and in brown adipocytes differentiated in culture.
Permanent Link: http://hdl.handle.net/11104/0040226