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Ontogenetic development of the G protein-mediated adenylyl cyclase signalling in rat brain
- 1.0142291 - FGU-C 20020012 RIV NL eng J - Journal Article
Ihnatovych, Ivanna - Novotný st., Jiří - Haugvicová, Renata - Bouřová, Lenka - Mareš, Pavel - Svoboda, Petr
Ontogenetic development of the G protein-mediated adenylyl cyclase signalling in rat brain.
Developmental Brain Research. Roč. 133, č. 1 (2002), s. 69-75. ISSN 0165-3806
R&D Projects: GA ČR GA309/99/0207; GA ČR GA305/00/1660; GA ČR GA309/01/0255
Institutional research plan: CEZ:AV0Z5011922
Keywords : adenylyl cyclase * rat brain * development
Subject RIV: FH - Neurology
Impact factor: 1.562, year: 2002
Maturation of the brain adenylyl cyclase (AC) signalling system was investigated in the developing rat cortex, thalamus and hippocampus. Comparison of results of the structural and functional analyses of AC signalling system revealed a clear dissociation between the increase in the amount of varioous AC isoforms and the decrease of total G-protein mediated enzyme activities between PD 12 and adulthood.
Permanent Link: http://hdl.handle.net/11104/0039997
Number of the records: 1