0142171 - FGU-C 20010225 RIV US eng J - Journal Article
Novotný st., Jiří - Bouřová, Lenka - Kolář, František - Svoboda, Petr
Membrane-bound and cytosolic forms of heterotrimeric G proteins in young and adult rat myocardium: influence of neonatal hypo- and hyperthyroidism.
Journal of Cellular Biochemistry. Roč. 82, č. 2 (2001), s. 215-224. ISSN 0730-2312. E-ISSN 1097-4644
R&D Projects: GA ČR GA305/00/1660; GA MŠMT VS97099
Institutional research plan: CEZ:AV0Z5011922
Keywords : development * G proteins * young and adult rat myocardium
Subject RIV: CD - Macromolecular Chemistry
Impact factor: 2.536, year: 2001

The distribution of membrane-bound a cytosolic forms of trimeric G proteins was analyzed in preparations from ventricular myocardium derived from young hypo- or hyperthyroid rats and adult previously hypo- or hyperthyroid rats by quantitative immunoblotting. Most of tested G protein subunits were present not only in membranes but at least partially also in the cytosol. The membrane-cytosol balance of some myocardial G proteins was selectively affected by neonatal hypo- and hyperthyroidism.
Permanent Link: http://hdl.handle.net/11104/0039880