The effect of nonsteroidal anti-inflammatory drugs ibuprofen, flurbiprofen, and diclofenac on in vitro and in vivo growth of mouse fibrosarcoma

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SYSNO ASEP	0126748
Document Type	J - Journal Article
R&D Document Type	Journal Article
Subsidiary J	Ostatní články
Title	The effect of nonsteroidal anti-inflammatory drugs ibuprofen, flurbiprofen, and diclofenac on in vitro and in vivo growth of mouse fibrosarcoma
Author(s)	Hoferová, Zuzana (BFU-R)_RID Fedoročko, P. (SK) Hofmanová, Jiřina (BFU-R)_{RID, ORCID} Hofer, Michal (BFU-R)_{RID, ORCID} Znojil, V. (CZ) Minksová, Kateřina (BFU-R) Souček, Karel (BFU-R)_{RID, ORCID} Egyed, A. (AT) Kozubík, Alois (BFU-R)_{RID, ORCID}
Source Title	Cancer Investigation. - : Taylor & Francis - ISSN 0735-7907 Roč. 20, č. 4 (2002), s. 490-498
Number of pages	9 s.
Language	eng - English
Country	US - United States
Keywords	cyclooxygenase (COX) inhibitors ; fibrosarcoma cells
Subject RIV	BO - Biophysics
R&D Projects	IBS5004009 GA AV ČR - Academy of Sciences of the Czech Republic (AV ČR)
CEZ	AV0Z5004920 - BFU-R
Annotation	Three different cyclooxygenase (COX) inhibitors were found to inhibit growth of transplanted fibrosarcoma in mice. Their antitumor effect is supposed to comprise both direct action of COX inhibitors on fibrosarcoma cells and indirect effects that are presumably mediated by extratumoral sources.
Workplace	Institute of Biophysics
Contact	Jana Poláková, polakova@ibp.cz, Tel.: 541 517 244
Year of Publishing	2003

Number of the records: 1