Pharmaco attributes of dioleoylphosphatidylethanolamine/cholesterylhemisuccinate liposomes containing different types of cleavable lipopolymers

Number of the records: 1

1.

SYSNO ASEP	0105813
Document Type	J - Journal Article
R&D Document Type	Journal Article
Subsidiary J	Ostatní články
Title	Pharmaco attributes of dioleoylphosphatidylethanolamine/cholesterylhemisuccinate liposomes containing different types of cleavable lipopolymers
Title	Farmakologické vlastnosti liposomů na bázi dioleoylfosfatidylethanolamine/cholesterylhemisukcinátů s různými typy štěpitelných lipopolymerů
Author(s)	Zhang, J. X. (CA) Zalipsky, S. (US) Mullah, N. (US) Pechar, Michal (UMCH-V)_{RID, ORCID} Allen, T. M. (CA)
Source Title	Pharmacological Research. - : Elsevier - ISSN 1043-6618 Roč. 49, č. 2 (2004), s. 185-198
Number of pages	14 s.
Language	eng - English
Country	GB - United Kingdom
Keywords	pH-sensitive liposomes ; polyethyleneglycol ; pharmacokinetics
Subject RIV	CD - Macromolecular Chemistry
R&D Projects	KSK4050111 GA AV ČR - Academy of Sciences of the Czech Republic (AV ČR)
CEZ	AV0Z4050913 - UMCH-V
Annotation	Various amounts of one of three different types of cleavable methoxy polyethylene glycol (mPEG)-phospholipids or of a non-cleavable counterpart (mPEG-DSPE) were included into pH-sensitive liposome formulations containing dioleoylphosphatidylethanolamine and cholesterylhemisuccinate at a 6:4 molar ratio, and the effect on plasma clearance and contents release rates was determined.
Workplace	Institute of Macromolecular Chemistry
Contact	Eva Čechová, cechova@imc.cas.cz ; Tel.: 296 809 358
Year of Publishing	2005

Number of the records: 1