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Relation between the kinetic and equilibrium quantities in size-exclusion chromatography

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    SYSNO ASEP0105700
    Document TypeJ - Journal Article
    R&D Document TypeJournal Article
    Subsidiary JOstatní články
    TitleRelation between the kinetic and equilibrium quantities in size-exclusion chromatography
    TitleVztahy mezi kinetickými a rovnovážnými veličinami v rozměrově vylučovací chromatografii
    Author(s) Netopilík, Miloš (UMCH-V) RID
    Source TitleJournal of Chromatography A. - : Elsevier - ISSN 0021-9673
    Roč. 1038, 1-2 (2004), s. 67-75
    Number of pages9 s.
    Languageeng - English
    CountryNL - Netherlands
    Keywordschromatography theory ; mobile and solid phase ; adsorption and desorption
    Subject RIVCD - Macromolecular Chemistry
    CEZAV0Z4050913 - UMCH-V
    AnnotationSeparation mechanisms in the adsorption and size-exclusion chromatography (SEC) modes are equivalent and can be described in terms of a mean fraction of the analyte in mobile phase (MP) and the number of interactions of molecules of the analyte in MP and in pores of/on the solid phase (SP). This is derived by comparing a recent theory of SEC with the theory of Giddings and Eyring for the adsorption chromatography. The elution volume is the excluded volume divided by the mean fraction of the analyte in mobile phase. Relations between the probabilities of adsorption and desorption of the molecule and the fractions of the analyte in MP and SP were derived.
    WorkplaceInstitute of Macromolecular Chemistry
    ContactEva Čechová, cechova@imc.cas.cz ; Tel.: 296 809 358
    Year of Publishing2005
Number of the records: 1  

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