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Scale-Up to High Shear Wet Granulation Process
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SYSNO ASEP 0104947 Document Type C - Proceedings Paper (int. conf.) R&D Document Type Conference Paper Title Scale-Up to High Shear Wet Granulation Process Title Zvětšování měřítka vlhkého granulačného procesu s vysokým smykem Author(s) Belohlav, Z. (CZ)
Brenková, L. (CZ)
Durdil, P. (CZ)
Hanika, Jiří (UCHP-M) RID, ORCID, SAI
Lehotský, M. (CZ)
Rápek, P. (CZ)
Tomášek, V. (CZ)Source Title Summaries 3, Hydrodynamic Processes.. - Praha : Process Engineering Publisher, 2004 - ISBN 80-86059-40-5 Pages s. 993 Number of pages 1 s. Publication form CD-ROM - CD-ROM Action International Congress of Chemical and Process Engineering CHISA 2004 /16./ Event date 22.08.2004-26.08.2004 VEvent location Praha Country CZ - Czech Republic Event type EUR Language eng - English Country CZ - Czech Republic Keywords scale-up ; pharmaceutical industry ; granulation process Subject RIV CI - Industrial Chemistry, Chemical Engineering CEZ AV0Z4072921 - UCHP-M Annotation Mathematical modelling of granulation process represents a useful tool for rules of safe scale-up procedure definition. The same granulator filling ratio, geometrical similitude of granulator and its impeller and chopper, identical peripheral impeller velocity and identical conditions for heat transfer in case of constant all technological and operation parameters are the most important conditions for successful data scale-up. Workplace Institute of Chemical Process Fundamentals Contact Eva Jirsová, jirsova@icpf.cas.cz, Tel.: 220 390 227 Year of Publishing 2005
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