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Theoretical study of the guanine → 6-thioguanine substitution in duplexes, triplexes, and tetraplexes

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    SYSNO ASEP0104647
    Document TypeJ - Journal Article
    R&D Document TypeJournal Article
    Subsidiary JOstatní články
    TitleTheoretical study of the guanine → 6-thioguanine substitution in duplexes, triplexes, and tetraplexes
    TitleTeoretická studie substituce guanin → 6-thioguanin v duplexech, triplexech a tetraplexech
    Author(s) Špačková, Naďa (BFU-R) RID
    Cubero, E. (ES)
    Šponer, Jiří (UFCH-W)
    Orozco, M. (ES)
    Source TitleJournal of the American Chemical Society. - : American Chemical Society - ISSN 0002-7863
    Roč. 126, č. 44 (2004), s. 14642-14650
    Number of pages9 s.
    Languageeng - English
    CountryUS - United States
    Keywords6-thioguanine ; molecular dynamics simulations ; thermodynamic integration
    Subject RIVBO - Biophysics
    R&D ProjectsLN00A016 GA MŠMT - Ministry of Education, Youth and Sports (MEYS)
    CEZAV0Z5004920 - BFU-R
    AnnotationMolecular dynamics and thermodynamic integration calculations have been carried out on a set of G-rich single-strand, duplex, triplex, and quadruplex DNAs to study the structural and stability changes connected with the guanine to 6-thioguanine mutation.
    WorkplaceInstitute of Biophysics
    ContactJana Poláková, polakova@ibp.cz, Tel.: 541 517 244
    Year of Publishing2005
Number of the records: 1  

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