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Linkage mapping of the MC3R gene to porcine chromosome 17

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    0102925 - UZFG-Y 20043081 RIV US eng J - Journal Article
    Civáňová, K. - Knoll, Aleš - Rohrer, G. A. - Čepica, Stanislav
    Linkage mapping of the MC3R gene to porcine chromosome 17.
    [Vazbové mapování genu MC3R na chromozóm 17 prasete.]
    Animal Genetics. Roč. 35, - (2004), s. 467-469. ISSN 0268-9146. E-ISSN 1365-2052
    R&D Projects: GA ČR GD523/03/H076
    Institutional research plan: CEZ:AV0Z5045916
    Keywords : chromosome 17
    Subject RIV: EB - Genetics ; Molecular Biology
    Impact factor: 3.108, year: 2004

    A fragment of porcine MC3R gene for melanocortin 3 receptor was cloned and sequenced. PCR-RFLP was performed and biallelic polymorphism was detected with MnlI and DdeI. Mendelian inheritance was conformed in the USDA-MARC backcross pedigree. Two-point linkage analysis identified the most significant linkage with SE47623 and multi-point analysis localised the MC3R marker on the USDA-MARC linkage map to SSC17 position 62.5 cM

    Byl klonován a sekvenován fragment MC3R genu pro melanocortin 3 receptor. Bylo provedeno PCR-RFLP a pomocí MnlI a DdeI byly detekovány dvoualelové polymorfismy. Mendelistická dědičnost byla prokázána na backcross rodokmenu USDA-MARC. Nejvýznamnější vazba byla pomocí dvoubodové analýzy identifikována s SE47623 a mnohobodová analýza lokalizovala MC3R maker na vazbové mapě USDA-MARC na chromozóm 17 do pozice 62.5 cM
    Permanent Link: http://hdl.handle.net/11104/0010262

     
     

Number of the records: 1  

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