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Biphasic action of vigabatrin on cortical epileptic after-discharges in rats
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SYSNO ASEP 0102548 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Ostatní články Title Biphasic action of vigabatrin on cortical epileptic after-discharges in rats Title Dvoufázový účinek vigabatrinu na korové epileptické následné výboje u potkanů Author(s) Mareš, Pavel (FGU-C) RID, ORCID
Šlamberová, Romana (FGU-C)Source Title Naunyn-Schmiedeberg's Archives of Pharmacology. - : Springer - ISSN 0028-1298
Roč. 369, č. 3 (2004), s. 305-311Number of pages 7 s. Language eng - English Country DE - Germany Keywords epileptic seizures ; electrical stimulation ; sensorimotor cortex Subject RIV ED - Physiology R&D Projects GA309/00/1643 GA ČR - Czech Science Foundation (CSF) CEZ AV0Z5011922 - FGU-C Annotation The time course of the anticonvulsant effect of vigabatrin against cortically induced epileptic after-discharges was studied in rats. Our cortical model of seizure demonstrates that the sequence of pro- and anticonvulsant actions of vigabatrin is not restricted to seizures of limbic origin and might represent a general phenomenon Workplace Institute of Physiology Contact Lucie Trajhanová, lucie.trajhanova@fgu.cas.cz, Tel.: 241 062 400 Year of Publishing 2005
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