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Polymer-coated polyethyleneimine/DNA complexes designed for triggered activation by intracellular reduction

  1. 1.
    0101406 - UMCH-V 20043126 RIV GB eng J - Journal Article
    Carlisle, R. C. - Etrych, Tomáš - Briggs, S. S. - Preece, J. A. - Ulbrich, Karel - Seymour, L. W.
    Polymer-coated polyethyleneimine/DNA complexes designed for triggered activation by intracellular reduction.
    [Polymerem kryté komplexy polyethylenimic/DNA navržené pro aktivaci spouštěnou vnitrobuněčnou redukcí.]
    Journal of Gene Medicine. Roč. 6, č. 3 (2004), s. 337-344. ISSN 1099-498X. E-ISSN 1521-2254
    R&D Projects: GA AV ČR KSK4055109
    Institutional research plan: CEZ:AV0Z4050913
    Keywords : reduction-triggered * transfection * polyethylenimine
    Subject RIV: CC - Organic Chemistry
    Impact factor: 3.224, year: 2004

    Linkage of hydrophilic polymer coating to PEI/DNA complexes via reducible disulphide bonds allows of fulfilling the contradictory requirements for extracellular stability and intracellular activity.

    Napojení hydrofilního obalu kolem PEI/DNA komplexu prostřednictvím disulfidické vazby umožňuje splnit protichůdné požadavky mimobuněčné stability a vnitrobuněčné aktivity.
    Permanent Link: http://hdl.handle.net/11104/0008839
     
Number of the records: 1  

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