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Effect of hyaluronidase and PEG chain conjugation on the biologic and antitumour activity of RNase A
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SYSNO ASEP 0100592 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Ostatní články Title Effect of hyaluronidase and PEG chain conjugation on the biologic and antitumour activity of RNase A Title Působení ribonukleasy A konjugované hyaluronidasou a PEG na biologické a protinádorové aktivity Author(s) Matoušek, Josef (UZFG-Y) RID
Poučková, P. (CZ)
Hloušková, D. (CZ)
Zadinová, M. (CZ)
Souček, J. (CZ)
Škvor, J. (CZ)Source Title Journal of Controlled Release. - : Elsevier - ISSN 0168-3659
Roč. 94, - (2004), s. 401-410Number of pages 10 s. Language eng - English Country US - United States Keywords antitumour ; aspermatogenesis ; embryotoxicity Subject RIV EB - Genetics ; Molecular Biology R&D Projects GA523/01/0114 GA ČR - Czech Science Foundation (CSF) CEZ AV0Z5045916 - UZFG-Y Annotation Subcutaneous application of bovine RNase A conjugated to HYase (bovine hyaluronidase), polyethylene glycol(PEG)and HYase+PEG resulted in a marker reduction of the width of the spermatogenic layers of the mouse testes. The number of sperms in caput epididymidis was significantly desreased in mice injected with conjugated RNase A Workplace Institute of Animal Physiology and Genetics Contact Jana Zásmětová, knihovna@iapg.cas.cz, Tel.: 315 639 554 Year of Publishing 2005
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