0100391 - MBU-M 20040081 RIV US eng J - Journal Article
Osička, Radim - Procházková, Kateřina - Šulc, Miroslav - Linhartová, Irena - Havlíček, Vladimír - Šebo, Peter
A Novel ,,Clip-and-link,,Activity of Repeat in Toxin (RTX) Proteins from Gram-negative Pathogens.
[Nová „clip-and-link“ aktivita opakované sekvence v toxickém RTX proteinu z gram-negativních patogenů.]
Journal of Biological Chemistry. Roč. 279, č. 24 (2004), s. 24944-24956. ISSN 0021-9258. E-ISSN 1083-351X
R&D Projects: GA ČR GA310/02/1448
Grant - others:GA Howard Hughes Medical Institute International Research Scholarship Award(XX) 55000334
Keywords : frpc * rtx * d510a
Subject RIV: EE - Microbiology, Virology
Impact factor: 6.355, year: 2004

A novel type of autocatalytic cleavage of the peptide bond between aspartate and proline residues of RTX protein FrpC from Neisseria menigitidis was found. The results define a protein cleavage and cross-linking module of a new class of RTX proteins of Gram-negative pathogens.

Charakterizovali jsme zcela novou biochemickou aktivitu RTX proteinů spočívající ve štěpení peptidové vazby mezi zbytky aspartátu a prolinu.
Permanent Link: http://hdl.handle.net/11104/0007893