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Special type of pheromone-induced invasive growth in Saccharomyces cerevisiae
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SYSNO ASEP 0084800 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Ostatní články Title Special type of pheromone-induced invasive growth in Saccharomyces cerevisiae Title Zvláštní typ feromonového zarůstání v Saccharomyces cerevisiae Author(s) Frýdlová, Ivana (MBU-M)
Basler, Marek (MBU-M)
Vašicová, Pavla (MBU-M) RID
Malcová-Janatová, Ivana (MBU-M) RID
Hašek, Jiří (MBU-M) RID, ORCIDSource Title Current Genetics. - : Springer - ISSN 0172-8083
Roč. 52, - (2007), s. 87-95Number of pages 9 s. Language eng - English Country DE - Germany Keywords agglutinins ; isw2 complex ; aga1 Subject RIV EE - Microbiology, Virology R&D Projects IAA5020409 GA AV ČR - Academy of Sciences of the Czech Republic (AV ČR) CEZ AV0Z50200510 - MBU-M (2005-2011) Annotation Many features of the invasion of MATAlfa cells lacking the Isw2 protein, a subunit of ISW2 chromatin remodelling complex, resemble pheromone-induced invasive growth. We show that pheromone induced surface protein Aga1 is necessary for this invasive behaviour. We also found that this invasion specifically requires Fus3 kinase whose function cannot be substituted by Kss1 kinase. Fus3p and Aga1p dependence distinguishes the isw2Gamma MATAlfa cells invasion from the pheromone-induced invasive growth. We suggest that partial dependence of the isw2Gamma MATAlfa invasion on these proteins corresponds to a weaker pheromone response of this mutant Workplace Institute of Microbiology Contact Eliška Spurná, eliska.spurna@biomed.cas.cz, Tel.: 241 062 231 Year of Publishing 2008
Number of the records: 1