- RNA Kink-turns as flexible molecular elbows relevant to ribosome func…
Number of the records: 1  

RNA Kink-turns as flexible molecular elbows relevant to ribosome function

  1. 1.
    SYSNO ASEP0029357
    Document TypeA - Abstract
    R&D Document TypeThe record was not marked in the RIV
    R&D Document TypeNení vybrán druh dokumentu
    TitleRNA Kink-turns as flexible molecular elbows relevant to ribosome function
    TitleRNA Kink-turn motivy jako flexibilní molekulární klouby důležité pro funkci ribozómu
    Author(s) Rázga, Filip (BFU-R)
    Zacharias, Martin (DE)
    Réblová, Kamila (BFU-R)
    Koča, Jaroslav (CZ)
    Šponer, Jiří (BFU-R) RID, ORCID
    Source TitleAbstracts. - Brno, 2005
    s. 17
    Number of pages1 s.
    ActionKonference mladých vědeckých pracovníků "Strukturní biofyzika makromolekul"
    Event date16.12.2005
    CountryCZ - Czech Republic
    Event typeCST
    Languageeng - English
    CountryCZ - Czech Republic
    KeywordsRNA Kink turn ; RNA flexibility ; ribosome function
    Subject RIVBO - Biophysics
    R&D ProjectsGD204/03/H016 GA ČR - Czech Science Foundation (CSF)
    CEZAV0Z50040507 - BFU-R (2005-2011)
    AnnotationExplicit-solvent Molecular Dynamics (MD) simulations were carried out for three K-turns (Kt) from 23S rRNA, i.e., Kt-38 located at the A-site finger base, Kt-42 located at the L7/L12 stalk base, and Kt-58 located in Domain III and for K-turn of human U4 snRNA. The presence of K-turns at key functional sites in the ribosome (e.g., A-site finger and L7/L12 stalk) suggests that some K-turns can confer flexibility on RNA protuberances that regulate the traversal of tRNAs during translocation. MD simulations demonstrated that the K-turns can act as flexible molecular elbows.
    WorkplaceInstitute of Biophysics
    ContactJana Poláková, polakova@ibp.cz, Tel.: 541 517 244
    Year of Publishing2006
Number of the records: 1  

  This site uses cookies to make them easier to browse. Learn more about how we use cookies.