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The intracellular distribution of HPMA-based polymeric prodrugs strongly influences their cytotoxic effects

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    0028296 - MBÚ 2006 RIV SIGLE GB eng C - Conference Paper (international conference)
    Hovorka, Ondřej - Strohalm, Jiří - Etrych, Tomáš - Ulbrich, Karel - Říhová, Blanka
    The intracellular distribution of HPMA-based polymeric prodrugs strongly influences their cytotoxic effects.
    [Intracelulární distribuce polymerních léčiv na bázi HMPA silně ovlivňuje jejich cytostatický efekt.]
    Nanomedicines of the Future – Scotland-Czech Republic Drug Delivery Workshop. Glasgow, 2005, s. 20-20.
    [Nanomedicines of the Future – Scotland-Czech Republic Drug Delivery Workshop. Glasgow (GB), 18.11.2005-18.11.2005]
    Institutional research plan: CEZ:AV0Z50200510
    Keywords : hpma * doxorubicin
    Subject RIV: EE - Microbiology, Virology

    The composition of the spacer and the way of doxorubicin binding strongly influences intracellular distribution of polymeric drugs and in that way the mechanism of cell death

    Tato práce ukázala, že složení postranního řetězce a způsob vazby doxorubicinu silně ovlivňuje intracelulární distribuci polymerních léčiv a tím i mechanismus buněčné smrti
    Permanent Link: http://hdl.handle.net/11104/0118243

     
     
Number of the records: 1  

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