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Behavioral evidence that segregation and representation are dissociable hippocampal functions
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SYSNO ASEP 0025013 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Ostatní články Title Behavioral evidence that segregation and representation are dissociable hippocampal functions Title Behaviorální důkaz, že segregace a reprezentace informace jsou oddělitelné funkce hipokampu Author(s) Kubík, Štěpán (FGU-C) RID, ORCID
Fenton, André Antonio (FGU-C)Source Title Journal of Neuroscience. - : Society for Neuroscience - ISSN 0270-6474
Roč. 25, č. 40 (2005), s. 9205-9212Number of pages 8 s. Language eng - English Country US - United States Keywords acquisition ; retention ; pattern separation Subject RIV FH - Neurology CEZ AV0Z5011922 - FGU-C Annotation The hypothesis that the rodent hippocampus performs two dissociable functions, segregation and representation of information was addressed by testing the following predictions: (1) TTX injection into one hippocampus would spare learning but (2) impair retrieval of a place response in the water maze, which has a high associative representational demand but a low demand for segregation; (3) the injection would impair learning but (4) spare retrieval of place avoidance in the rotating arena filled with water, which has a high demand for stimulus segregation but a low associative representational demand. All four predictions were confirmed Workplace Institute of Physiology Contact Lucie Trajhanová, lucie.trajhanova@fgu.cas.cz, Tel.: 241 062 400 Year of Publishing 2006
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