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Asparagine, valine, and threonine in the third extracellular loop of muscarinic receptor have essential roles in the positive cooperativity of strychnine-like allosteric modulators

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    0025009 - FGÚ 2006 RIV US eng J - Journal Article
    Jakubík, Jan - Krejčí, Alena - Doležal, Vladimír
    Asparagine, valine, and threonine in the third extracellular loop of muscarinic receptor have essential roles in the positive cooperativity of strychnine-like allosteric modulators.
    [Asparagin, valin a threonin ve třetí extracelulární kličce muskarinového acetylcholinového receptoru mají zásadní úlohu pro pozitivní kooperativitu alosterických modulátorů podobných strychninu.]
    Journal of Pharmacology and Experimental Therapeutics. Roč. 313, č. 2 (2005), s. 688-696. ISSN 0022-3565. E-ISSN 1521-0103
    R&D Projects: GA ČR(CZ) GA309/02/1331; GA ČR(CZ) GP305/02/D090; GA AV ČR(CZ) IAA5011306; GA MŠMT(CZ) LC554
    Institutional research plan: CEZ:AV0Z50110509
    Keywords : muscarinic receptors * positive cooperativity * mutation
    Subject RIV: ED - Physiology
    Impact factor: 4.098, year: 2005

    Permanent Link: http://hdl.handle.net/11104/0115462
     
Number of the records: 1  

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