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Glycosyl azide-a novel substrate for enzymatic transgycosylations
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SYSNO ASEP 0024323 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Ostatní články Title Glycosyl azide-a novel substrate for enzymatic transgycosylations Title Glykosylazid - novy substrát pro enzymatické transglykosylace Author(s) Fialová, Pavla (MBU-M)
Carmona, A. T. (ES)
Robina, I. (ES)
Ettrich, R. (CZ)
Sedmera, Petr (MBU-M)
Přikrylová, Věra (MBU-M)
Hušáková, Lucie (MBU-M)
Křen, Vladimír (MBU-M) RID, ORCIDSource Title Tetrahedron Letters. - : Elsevier - ISSN 0040-4039
Roč. 46, - (2005), s. 8715-8718Number of pages 4 s. Language eng - English Country GB - United Kingdom Keywords enzyme catalysis ; glycosyl azide ; molecular modelling Subject RIV EE - Microbiology, Virology R&D Projects GA203/05/0172 GA ČR - Czech Science Foundation (CSF) OC D25.002 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) CEZ AV0Z50200510 - MBU-M (2005-2011) Annotation Glycosyl azides are new efficient donors for glycosidases. Their high water solubility facilitates transglycosylations with comparable or better yields than common O-glycosides. The azido group totally changes the beta-GalNAc-ase/beta-GlcNAc-ase ratio in beta-N-acetylhexosaminidases, contrary to all known aglycons Workplace Institute of Microbiology Contact Eliška Spurná, eliska.spurna@biomed.cas.cz, Tel.: 241 062 231 Year of Publishing 2006
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