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Bimetallic nanowires on laser-patterned PEN as promising biomaterials
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SYSNO ASEP 0547750 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Bimetallic nanowires on laser-patterned PEN as promising biomaterials Author(s) Pryjmaková, J. (CZ)
Kaimlová, M. (CZ)
Vokatá, B. (CZ)
Hubáček, Tomáš (BC-A) RID
Slepička, P. (CZ)
Svorčík, V. (CZ)
Siegel, J. (CZ)Article number 2285 Source Title Nanomaterials. - : MDPI
Roč. 11, č. 9 (2021)Number of pages 15 s. Language eng - English Country CH - Switzerland Keywords surface modification ; nanostructure ; polymer ; bimetallic nanowires ; biocompatibility ; antibacterial properties Subject RIV JP - Industrial Processing OECD category Materials engineering Method of publishing Open access Institutional support BC-A - RVO:60077344 UT WOS 000700160800001 EID SCOPUS 85114084317 DOI 10.3390/nano11092285 Annotation As inflammation frequently occurs after the implantation of a medical device, biocompatible, antibacterial materials must be used. Polymer-metal nanocomposites are promising materials. Here we prepared enhanced polyethylene naphthalate (PEN) using surface modification techniques and investigated its suitability for biomedical applications. The PEN was modified by a KrF laser forming periodic ripple patterns with specific surface characteristics. Next, Au/Ag nanowires were deposited onto the patterned PEN using vacuum evaporation. Atomic force microscopy confirmed that the surface morphology of the modified PEN changed accordingly with the incidence angle of the laser beam. Energy-dispersive X-ray spectroscopy showed that the distribution of the selected metals was dependent on the evaporation technique. Our bimetallic nanowires appear to be promising antibacterial agents due to the presence of antibacterial noble metals. The antibacterial effect of the prepared Au/Ag nanowires against E. coli and S. epidermidis was demonstrated using 24 h incubation with a drop plate test. Moreover, a WST-1 cytotoxicity test that was performed to determine the toxicity of the nanowires showed that the materials could be considered non-toxic. Collectively, these results suggest that prepared Au/Ag nanostructures are effective, biocompatible surface coatings for use in medical devices. Workplace Biology Centre (since 2006) Contact Dana Hypšová, eje@eje.cz, Tel.: 387 775 214 Year of Publishing 2022 Electronic address https://www.mdpi.com/2079-4991/11/9/2285
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