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Xanthones content in swertia multicaulis D. Don from Nepal
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SYSNO ASEP 0490943 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Xanthones content in swertia multicaulis D. Don from Nepal Author(s) Timsina, Binu (UEK-B) RID, SAI, ORCID, RID
Kindlmann, Pavel (UEK-B) RID, ORCID, SAI
Rokaya, Maan Bahadur (UEK-B) RID, ORCID, SAI
Vrchotová, Naděžda (UEK-B) RID, SAI, ORCID
Tříska, Jan (UEK-B) RID, ORCID, SAI
Horník, Štěpán (UCHP-M) ORCID, RID, SAI
Sýkora, Jan (UCHP-M) RID, ORCID, SAINumber of authors 7 Article number 1067 Source Title Molecules. - : MDPI
Roč. 23, č. 5 (2018)Number of pages 8 s. Language eng - English Country CH - Switzerland Keywords Gentianaceae ; hplc ; lc–ms ; nmr ; Phytochemistry ; Secondary metabolites ; Swertia Subject RIV EH - Ecology, Behaviour OECD category Biodiversity conservation Subject RIV - cooperation Institute of Chemical Process Fundamentals - Analytical Chemistry, Separation R&D Projects LO1415 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) Institutional support UEK-B - RVO:86652079 ; UCHP-M - RVO:67985858 UT WOS 000435204000082 EID SCOPUS 85046635552 DOI 10.3390/molecules23051067 Annotation The medicinal plant Swertia multicaulis D. Don was collected in Rasuwa District (Nepal) and the xanthone content of its ethyl acetate extracts was studied. The total amount of xanthones in S. multicaulis determined by HPLC reaches almost 13 g of xanthones per 1 kg of dry matter. The identification of xanthones in S. multicaulis was achieved by a combination of HPLC, LC–MS and LC–NMR. The final assignment of the individual chemical structures was provided by NMR, supported by preparative HPLC. In eight chromatographic peaks, four major xanthones were identified—1,3-dihydroxy-5,8-dimethoxyxanthone, 1-hydroxy-3,5,8-trimethoxyxanthone, bellidifolin (1,5,8-tri-hydroxy-3-methoxyxanthone), and decussatin (1-hydroxy-3,7,8-trimethoxyxanthone). Workplace Global Change Research Institute Contact Nikola Šviková, svikova.n@czechglobe.cz, Tel.: 511 192 268 Year of Publishing 2019
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