Number of the records: 1
Evc Regulates a Symmetrical Response to Shh Signaling in Molar Development
- 1.
SYSNO ASEP 0396271 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Evc Regulates a Symmetrical Response to Shh Signaling in Molar Development Author(s) Nakatomi, M. (GB)
Hovořáková, Mária (UEM-P) RID
Gritli-Linde, A. (SE)
Blair, H. J. (GB)
MacArthur, K. (GB)
Peterka, Miroslav (UEM-P) RID
Lesot, H. (FR)
Peterková, Renata (UEM-P) RID
Ruiz-Perez, V. L. (ES)
Goodship, J. A. (GB)
Peters, H. (GB)Number of authors 11 Source Title Journal of Dental Research. - : Sage - ISSN 0022-0345
Roč. 92, č. 3 (2013), s. 222-228Number of pages 7 s. Language eng - English Country US - United States Keywords odontogenesis ; organogenesis ; embryonic and fetal development Subject RIV EA - Cell Biology R&D Projects GA304/09/1579 GA ČR - Czech Science Foundation (CSF) GAP305/12/1766 GA ČR - Czech Science Foundation (CSF) Institutional support UEM-P - RVO:68378041 UT WOS 000314914100004 EID SCOPUS 84874044643 DOI 10.1177/0022034512471826 Annotation The observed growth abnormalities eventually manifest in first molar microdontia, disruption of molar segmentation and symmetry, root fusions, and delayed differentiation. Analysis of our data indicates that both spatially and temporally disrupted activities of the Shh pathway are the primary cause for the variable dental anomalies seen in patients with Ellis-van Creveld syndrome or Weyers acrodental dysostosis. Workplace Institute of Experimental Medicine Contact Lenka Koželská, lenka.kozelska@iem.cas.cz, Tel.: 241 062 218, 296 442 218 Year of Publishing 2014
Number of the records: 1