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Cruciform structures are a common DNA feature important for regulating biological processes
- 1.0365821 - BFÚ 2012 RIV GB eng J - Journal Article
Brázda, Václav - Laister, R.C. - Jagelská, Eva - Arrowsmith, Ch.
Cruciform structures are a common DNA feature important for regulating biological processes.
B M C Molecular Biology. Roč. 12, č. 33 (2011), s. 1-16. ISSN 1471-2199. E-ISSN 1471-2199
R&D Projects: GA ČR(CZ) GAP301/10/1211; GA MŠMT(CZ) LC06035
Institutional research plan: CEZ:AV0Z50040507; CEZ:AV0Z50040702
Keywords : cruciform structure * inverted repeat * protein-DNA binding
Subject RIV: BO - Biophysics
Impact factor: 2.857, year: 2011
DNA cruciforms play an important role in the regulation of natural processes involving DNA. These structures are formed by inverted repeats, and their stability is enhanced by DNA supercoiling. Cruciform structures are fundamentally important for a wide range of biological processes, including replication, regulation of gene expression, nucleosome structure and recombination. They also have been implicated in the evolution and development of diseases including cancer, Werner's syndrome and others.
Permanent Link: http://hdl.handle.net/11104/0200975
Number of the records: 1