Number of the records: 1  

Human plasma depletion techniques for label-free detection of low-abundance plasma proteins

  1. 1.
    SYSNO ASEP0356063
    Document TypeA - Abstract
    R&D Document TypeThe record was not marked in the RIV
    R&D Document TypeNení vybrán druh dokumentu
    TitleHuman plasma depletion techniques for label-free detection of low-abundance plasma proteins
    Author(s) Suttnar, J. (CZ)
    Bocková, Markéta (URE-Y)
    Pimková, K. (CZ)
    Májek, P. (CZ)
    Kotlín, R. (CZ)
    Homola, Jiří (URE-Y) RID
    Dyr, J. E. (CZ)
    Number of authors7
    Source TitleEUROPT(R)ODE X, X.Conference on Optical Chemical Sensors and Biosensors. - Praha : Institute of Photonics and Electronics AS CR, v.v.i, 2010 / Homola Jiří - ISBN 978-80-86269-20-7
    S. 238-238
    Number of pages1 s.
    ActionEUROPT(R)ODE X – X.Conference on Optical Chemical Sensors and Biosensors
    Event date28.03.2010-31.3.2010
    VEvent locationPraha
    CountryCZ - Czech Republic
    Event typeWRD
    Languageeng - English
    CountryCZ - Czech Republic
    Keywordsplasma imunodepletion ; peptide library ; surface plasmon resonance
    Subject RIVJB - Sensors, Measurment, Regulation
    R&D ProjectsKAN200670701 GA AV ČR - Academy of Sciences of the Czech Republic (AV ČR)
    CEZAV0Z20670512 - URE-Y (2005-2011)
    AnnotationThis paper describes the influence of blood plasma depletion on the performance of surface plasmon resonance sensor’s (SPR) estimation of proteins. Depletion method utilizing immobilized combinatorial hexapeptide ligand library or restricted acces material were used for samples pretreatment. The nonspecific binding of depleted plasma on the sensor surface was half as much lower than the binding of whole plasma with the same concentration of low-abundant proteins.
    WorkplaceInstitute of Radio Engineering and Electronics
    ContactPetr Vacek, vacek@ufe.cz, Tel.: 266 773 413, 266 773 438, 266 773 488
    Year of Publishing2011
Number of the records: 1  

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