Number of the records: 1
Antibody-targeted polymer conjugates of drugs
- 1.
SYSNO ASEP 0188309 Document Type C - Proceedings Paper (int. conf.) R&D Document Type Conference Paper Title Antibody-targeted polymer conjugates of drugs Author(s) Ulbrich, Karel (UMCH-V) RID
Etrych, Tomáš (UMCH-V) RID, ORCID
Chytil, Petr (UMCH-V) RID, ORCID
Jelínková, Markéta (MBU-M)
Říhová, Blanka (MBU-M) RIDSource Title Proceedings. - San Diego : Controlled Release Society, 2001 Pages s. no.0226 Number of pages 2 s. Publication form CD-ROM - CD-ROM Action International Symposium on Controlled Release of Bioactive Materials Event date 23.06.2001-27.06.2001 VEvent location San Diego Country US - United States Event type WRD Language eng - English Country US - United States Subject RIV ED - Physiology R&D Projects GV307/96/K226 GA ČR - Czech Science Foundation (CSF) KSK4055109 GA AV ČR - Academy of Sciences of the Czech Republic (AV ČR) CEZ AV0Z4050913 - UMCH-V Annotation The paper describes synthesis, in vitro drug release, and in vivo biological activity of antibody-targeted drugs based on HPMA copolymers. In the conjugates, cytotoxic drug doxorubicin is attached to the polymer via hydrolytically or enzymatically degradable spacers. The conjugates are being developed as potential anticancer drugs facilitating site-specific therapy. Workplace Institute of Macromolecular Chemistry Contact Eva Čechová, cechova@imc.cas.cz ; Tel.: 296 809 358 Year of Publishing 2002
Number of the records: 1