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Meso-Tetratolylporphyrins Substituted by Pyridinium Groups: Aggregation, Photophysical Properties and Complexation with DNA
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SYSNO ASEP 0101107 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Ostatní články Title Meso-Tetratolylporphyrins Substituted by Pyridinium Groups: Aggregation, Photophysical Properties and Complexation with DNA Title Meso-tetratolyl porfyrinové deriváty substituované pyridiovými skupinami: agregace, fotofyzikální vlastnosti a komplexace s DNA Author(s) Procházková, Kristina (UFCH-W)
Zelinger, Zdeněk (UFCH-W) RID, ORCID
Lang, Kamil (UACH-T) SAI, RID, ORCID
Kubát, Pavel (UFCH-W) RID, ORCID, SAISource Title Journal of Physical Organic Chemistry. - : Wiley - ISSN 0894-3230
Roč. 17, - (2004), s. 890-897Number of pages 8 s. Language eng - English Country GB - United Kingdom Keywords porphyrin ; aggregates ; DNA Subject RIV CF - Physical ; Theoretical Chemistry R&D Projects GA203/01/0634 GA ČR - Czech Science Foundation (CSF) GA203/02/0420 GA ČR - Czech Science Foundation (CSF) GA203/04/0426 GA ČR - Czech Science Foundation (CSF) CEZ AV0Z4040901 - UFCH-W AV0Z4032918 - UACH-T Annotation Aggregation of meso-tetratolylporphyrins substituted with two (P2), three (P3) and four (P4) pyridinium groups and their complexation with DNA were studied using UV/Vis and fluorescence spectroscopies, resonance light scattering and circular dichroism. In aqueous solution porphyrins P2-P4 existed in a monomeric form and/or as H- and J-aggregates. The concentration ratio of monomer/aggregates was controlled by the number of cationic substituents, by ionic strength and by temperature. Porphyrin monomers were externally bound to calf thymus DNA with the binding constant of /~106 M-1. Porphyrin aggregates formed chiral assemblies on the DNA template not affecting the duplex melting point. The lifetime of the triplet states of bound monomeric P3 and P4 increased after binding, however it did not prevent the formation of 1O2. Workplace J. Heyrovsky Institute of Physical Chemistry Contact Michaela Knapová, michaela.knapova@jh-inst.cas.cz, Tel.: 266 053 196 Year of Publishing 2005
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