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More than just an eagle killer: The freshwater cyanobacterium Aetokthonos hydrillicola produces highly toxic dolastatin derivatives

  1. 1.
    SYSNO0582359
    TitleMore than just an eagle killer: The freshwater cyanobacterium Aetokthonos hydrillicola produces highly toxic dolastatin derivatives
    Author(s) Schwark, M. (DE)
    Martinez Yerena, Jose A. (MBU-M)
    Roehrborn, K. (DE)
    Hrouzek, Pavel (MBU-M) ORCID
    Divoká, Petra (MBU-M)
    Štenclová, L. (CZ)
    Delawská, Kateřina (MBU-M) ORCID
    Enke, H. (DE)
    Vorreiter, C. (DE)
    Wiley, F. (US)
    Sippl, W. (DE)
    Sobotka, Roman (MBU-M) RID, ORCID
    Saha, Subhasish (MBU-M) ORCID
    Wilde, Susan B. (US)
    Mareš, Jan (MBU-M) ORCID
    Niedermeyer, T. H. J. (DE)
    Corespondence/seniorMareš, Jan - Korespondující autor
    Niedermeyer, T. H. J. - Korespondující autor
    Source Title Proceedings of the National Academy of Sciences of the United States of America. Roč. 120, č. 40 (2023). - : National Academy of Sciences
    Article numbere2219230120
    Document TypeČlánek v odborném periodiku
    Grant GC19-21649J GA ČR - Czech Science Foundation (CSF), CZ - Czech Republic
    Institutional supportMBU-M - RVO:61388971
    Languageeng
    CountryUS
    Keywords antineoplastic agents * marine * anticancer * analog * inhibition * tubulin * biosynthesis * efficacy * targets * binding * cyanotoxin * cytotoxicity * aetokthonostatin * dolastatin * biosynthesis
    Cooperating institutions Jihočeská univerzita, Přírodovědecká fakulta (Czech Republic)
    URLhttps://www.pnas.org/doi/10.1073/pnas.2219230120
    Permanent Linkhttps://hdl.handle.net/11104/0350572
     
Number of the records: 1  

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