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Chemical Blockage of the Mitochondrial Rhomboid Protease PARL by Novel Ketoamide Inhibitors Reveals Its Role in PINK1/Parkin-Dependent Mitophagy

  1. 1.
    SYSNO0566618
    TitleChemical Blockage of the Mitochondrial Rhomboid Protease PARL by Novel Ketoamide Inhibitors Reveals Its Role in PINK1/Parkin-Dependent Mitophagy
    Author(s) Poláchová, Edita (UOCHB-X) [250/25] ORCID
    Bach, Kathrin (UOCHB-X) [250/25]
    Heuten, E. (DE)
    Stanchev, Stancho (UOCHB-X) [250/25] RID, ORCID
    Tichá, Anežka (UOCHB-X) [250/25] ORCID, RID
    Lampe, P. (DE)
    Majer, Pavel (UOCHB-X) [390/39]
    Langer, T. (DE)
    Lemberg, M. K. (DE)
    Stříšovský, Kvido (UOCHB-X) [250/25] RID, ORCID
    Corespondence/seniorLemberg, M. K. - Korespondující autor
    Stříšovský, Kvido - Korespondující autor
    Source Title Journal of Medicinal Chemistry. Roč. 66, č. 1 (2023), s. 251-265. - : American Chemical Society
    Document TypeČlánek v odborném periodiku
    Grant LO1302 GA MŠMT - Ministry of Education, Youth and Sports (MEYS)
    EF16_019/0000729 GA MŠMT - Ministry of Education, Youth and Sports (MEYS), CZ - Czech Republic
    Institutional supportUOCHB-X - RVO:61388963
    Languageeng
    CountryUS
    Keywords lipid bilayer nanodiscs * membrane proteins * PINK1
    Cooperating institutions Univerzita Karlova v Praze (Czech Republic)
    URLhttps://doi.org/10.1021/acs.jmedchem.2c01092
    Permanent Linkhttps://hdl.handle.net/11104/0338165
     
Number of the records: 1  

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