Diagnostic Performance of a Noninvasive Breath Test for Colorectal Cancer: COBRA1 Study

Woodfield, G.; Belluomo, I.; Laponogov, I.; Veselkov, K. A.; Boshier, P. R.; Lin, G. P.; Myridakis, A.; Ayrton, O.; Španěl, Patrik; Vidal-Diez, A.; Romano, A.; Martin, J.; Marelli, L.; Groves, C.; Monahan, K.; Kontovounisios, C.; Saunders, B. P.; Cross, A.J.; Hanna, G. B.

doi:https://dx.doi.org/10.1053/j.gastro.2022.06.084

Number of the records: 1

Diagnostic Performance of a Noninvasive Breath Test for Colorectal Cancer: COBRA1 Study

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SYSNO ASEP	0562541
Document Type	J - Journal Article
R&D Document Type	Journal Article
Subsidiary J	Článek ve WOS
Title	Diagnostic Performance of a Noninvasive Breath Test for Colorectal Cancer: COBRA1 Study
Author(s)	Woodfield, G. (GB) Belluomo, I. (GB) Laponogov, I. (GB) Veselkov, K. A. (GB) Boshier, P. R. (GB) Lin, G. P. (GB) Myridakis, A. (GB) Ayrton, O. (GB) Španěl, Patrik (UFCH-W)_{RID, ORCID} Vidal-Diez, A. (GB) Romano, A. (GB) Martin, J. (GB) Marelli, L. (GB) Groves, C. (GB) Monahan, K. (GB) Kontovounisios, C. (GB) Saunders, B. P. (GB) Cross, A.J. (GB) Hanna, G. B. (GB)
Source Title	Gastroenterology. - : Elsevier - ISSN 0016-5085 Roč. 163, č. 5 (2022), s. 1447-1449
Number of pages	3 s.
Language	eng - English
Country	US - United States
Keywords	colorectal cancer (CRC) ; noninvasive breath test ; COBRA1 study
Subject RIV	CF - Physical ; Theoretical Chemistry
OECD category	Physical chemistry
Method of publishing	Open access
Institutional support	UFCH-W - RVO:61388955
UT WOS	000928460600005
EID SCOPUS	85138568338
DOI	10.1053/j.gastro.2022.06.084
Annotation	Colorectal cancer (CRC) is the third most common cancer globally. When diagnosed early, the 5-year survival rate is 92%, 2 yet 23% of CRCs are diagnosed at an advanced stage in the United Kingdom with a 5-year survival rate of 10%. Early CRC has symptoms that are shared with common benign conditions. Colonoscopy capacity is limited, and referring all symptomatic patients for colonoscopy would overwhelm available resources. An intermediate triage test to identify patients at risk of CRC could streamline referral pathways. A breath test based on detecting volatile organic compounds (VOCs) has the ideal characteristics for a triage tool because it is noninvasive, simple to undertake, and acceptable to patients of all ethnicities.
Workplace	J. Heyrovsky Institute of Physical Chemistry
Contact	Michaela Knapová, michaela.knapova@jh-inst.cas.cz, Tel.: 266 053 196
Year of Publishing	2023
Electronic address	https://hdl.handle.net/11104/0334853

Number of the records: 1