Poly(3,4-ethylenedioxythiophene):poly(styrene sulfonate) in antibacterial, tissue engineering and biosensors applications: progress, challenges and perspectives

Gupta, Sonal; Datt, R.; Mishra, A.; Tsoi, W. C.; Patra, A.; Bober, Patrycja

doi:https://dx.doi.org/10.1002/app.52663

Number of the records: 1

Poly(3,4-ethylenedioxythiophene):poly(styrene sulfonate) in antibacterial, tissue engineering and biosensors applications: progress, challenges and perspectives

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SYSNO ASEP	0559154
Document Type	J - Journal Article
R&D Document Type	Journal Article
Subsidiary J	Článek ve WOS
Title	Poly(3,4-ethylenedioxythiophene):poly(styrene sulfonate) in antibacterial, tissue engineering and biosensors applications: progress, challenges and perspectives
Author(s)	Gupta, Sonal (UMCH-V)_{RID, ORCID} Datt, R. (GB) Mishra, A. (IN) Tsoi, W. C. (GB) Patra, A. (IN) Bober, Patrycja (UMCH-V)_{RID, ORCID, SAI}
Article number	e52663
Source Title	Journal of Applied Polymer Science. - : Wiley - ISSN 0021-8995 Roč. 139, č. 30 (2022)
Number of pages	21 s.
Language	eng - English
Country	US - United States
Keywords	biocompatibility ; biomaterials ; biomedical applications
Subject RIV	CD - Macromolecular Chemistry
OECD category	Polymer science
R&D Projects	GA21-01401S GA ČR - Czech Science Foundation (CSF)
Method of publishing	Limited access
Institutional support	UMCH-V - RVO:61389013
UT WOS	000803137900001
EID SCOPUS	85130625293
DOI	10.1002/app.52663
Annotation	With the advancement of applications in biomedicines and bioelectronics, conducting polymers have attained huge significant attention. For such applications, poly(3,4-ethylenedioxythiophene):poly(styrene sulfonate) (PEDOT:PSS) is considered a potential conducting polymer because of its low cost, considerable stability, high conductivity and mechanical strength. Most importantly, its easy aqueous solution processability makes it more attractive. Over the last few years, PEDOT:PSS has been predominantly explored and investigated for different optoelectronic flexible devices, and recently it has been studied for biomedical applications. PEDOT:PSS based materials have made progress in biomedicines due to their properties such as biocompatibility, cell proliferation, antibacterial, nontoxicity and so forth. To adjust the desirable properties, special attention is required for altering the structure of PEDOT:PSS material. PEDOT:PSS offers excellent antibacterial properties against both gram-positive and gram-negative bacteria. Moreover, PEDOT:PSS demonstrates an important role in sensing human body humidity, pressure control, glucose detection, as well as employed in human sweat sensors. Besides these, PEDOT:PSS has been studied as a scaffold for endothelial cell preservation. There are several issues which need to be resolved in the future, such as improved biocompatibility and stability to explore the PEDOT:PSS based composite materials in biomedical applications. However, a related review article is lacking, directed on the PEDOT:PSS biomedical applications, namely, antibacterial, tissue engineering, and biosensing. Therefore, the current article summarizes importance of PEDOT:PSS for biomedical applications, and main emphasis is given to its recent advances, challenges and perspectives.
Workplace	Institute of Macromolecular Chemistry
Contact	Eva Čechová, cechova@imc.cas.cz ; Tel.: 296 809 358
Year of Publishing	2023
Electronic address	https://onlinelibrary.wiley.com/doi/10.1002/app.52663

Number of the records: 1