Number of the records: 1
New fluorescent-labelled nanoparticles: synthesis, characterization and interactions with cysteine and homocysteine to evaluate their stability in aqueous solution
- 1.
SYSNO ASEP 0536189 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title New fluorescent-labelled nanoparticles: synthesis, characterization and interactions with cysteine and homocysteine to evaluate their stability in aqueous solution Author(s) Scollo, Federica (UFCH-W) ORCID, RID
Seggio, M. (IT)
Torrisi, R. L. (IT)
Bua, R. O. (IT)
Zimbone, M. (IT)
Contino, A. (IT)
Maccarrone, G. (IT)Source Title Applied Nanoscience. - : Springer - ISSN 2190-5509
Roč. 10, č. 4 (2020), s. 1157-1172Number of pages 16 s. Language eng - English Country SA - Saudi Arabia Keywords silver nanoparticles ; gold nanoparticles ; amino-acids ; enantiorecognition ; enhancement ; copper(ii) ; adsorption ; histidine ; proteins ; cancer ; Fluorescent nanoparticles ; Dynamic light scattering ; Solution equilibria ; Spectroscopy ; Aggregation Subject RIV CF - Physical ; Theoretical Chemistry OECD category Physical chemistry Method of publishing Limited access Institutional support UFCH-W - RVO:61388955 UT WOS 000520600600014 EID SCOPUS 85077522769 DOI 10.1007/s13204-019-01241-9 Annotation Fluorescent-labelled nanoparticles conjugate the SPR of nanomaterials as well as the fluorescence properties of the capping dye. In this work, we report a study on the synthesis of fluorescent l-tyrosine (l-Tyr) and fluorescein (Fluo)-capped silver nanoparticles (AgNPs) carried out by a fine-tuning of the analytical concentration of the reagents. The AgNPs have been characterized by TEM, UV-Vis, ATR-FTIR, and photoluminescence (PL) spectroscopy and DLS. The adsorption of cysteine and homocysteine on the surface of the nanoparticles has been studied to evaluate their overall evolution in solution and their possible interactions with more complex systems, such as proteins. Opposed to homocysteine, cysteine induces aggregation either of tyrosine- and fluorescein-capped nanoparticles, which are therefore promising systems for the discrimination of biothiols. Furthermore, tyrosine-capped AgNPs, in spite of the better coordinating characteristics of this amino acid with respect to fluorescein, show aggregation abilities with cysteine greater than the fluorescein-capped ones that are unexpectedly more stable and thus less prone to aggregation phenomena. Workplace J. Heyrovsky Institute of Physical Chemistry Contact Michaela Knapová, michaela.knapova@jh-inst.cas.cz, Tel.: 266 053 196 Year of Publishing 2021 Electronic address http://hdl.handle.net/11104/0313999
Number of the records: 1