Tetrazole Ring Substitution at Carbon and Boron Sites of the Cobalt Bis(dicarbollide) Ion Available via Dipolar Cycloadditions

0535534 - ÚACH 2021 RIV US eng J - Journal Article
El Anwar, Suzan - Růžičková, Z. - Bavol, Dmytro - Fojt, Lukáš - Grüner, Bohumír
Tetrazole Ring Substitution at Carbon and Boron Sites of the Cobalt Bis(dicarbollide) Ion Available via Dipolar Cycloadditions.
Inorganic Chemistry. Roč. 59, č. 23 (2020), s. 17430-17442. ISSN 0020-1669. E-ISSN 1520-510X
R&D Projects: GA ČR(CZ) GA19-04630S
Grant - others:AV ČR(CZ) L200321851
Program: Program podpory perspektivníchlidských zdrojů - postdoktorandů
Institutional support: RVO:61388980 ; RVO:68081707
Keywords : Mixtures * Ethers * Boron * Vacuum * Ions
OECD category: Inorganic and nuclear chemistry; Biophysics (BFU-R)
Impact factor: 5.165, year: 2020
Method of publishing: Limited access
https://pubs.acs.org/doi/10.1021/acs.inorgchem.0c02719

Herein, we describe the synthesis of two families of compounds accessible from [3 + 2] cycloaddition reactions of known B8-substituted isonitrilium and new C1-alkylnitrile and C(1,1′)-dialkylnitrile derivatives of the [(1,2-C2B9H11)2-3,3′-Co(III)]- ion with an azide ion that produce a tetrazole ring substitution at the cobaltacarborane cage. In addition, we outline the important differences in reactivity observed for the two types [B-isonitrilium/C-(alkyl)nitrile] of cobaltacarborane derivatives. The first family of compounds described corresponds to C5-atom-boronated tetrazole rings, with the five-membered moiety in the second type being doubly substituted at the N1 and C5 positions. This substitution opens cobaltacarborane chemistry to a new type of functional group at the cage of potential utility as structural blocks for use in medicinal chemistry or materials science. Our study includes single-crystal X-ray structures of the starting nitriles and both families of tetrazole derivatives, and the structural features that arise from the substitutions are discussed.
Permanent Link: http://hdl.handle.net/11104/0314878


Research data: ACS publications, CCDC