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Comparative genomics of Leishmania (Mundinia)
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SYSNO ASEP 0518831 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Comparative genomics of Leishmania (Mundinia) Author(s) Butenko, Anzhelika (BC-A) RID, ORCID
Kostygov, A.Y. (CZ)
Sádlová, J. (CZ)
Kleschenko, Y. (RU)
Bečvář, T. (CZ)
Podešvová, L. (CZ)
Macedo, D. H. (CZ)
Zihala, D. (CZ)
Lukeš, Julius (BC-A) RID, ORCID
Bates, P.A. (GB)
Volf, P. (CZ)
Opperdoes, F. R. (BE)
Yurchenko, V. (CZ)Number of authors 13 Article number 726 Source Title BMC Genomics. - : BioMed Central - ISSN 1471-2164
Roč. 20, č. 1 (2019)Number of pages 12 s. Publication form Online - E Language eng - English Country US - United States Keywords phosphatidylinositol 3-phosphate recognition ; cutaneous leishmaniasis ; insect trypanosomatids ; heme-biosynthesis ; lipophosphoglycan ; alignment ; gene ; annotation ; metabolism ; enriettii ; Whole genome sequencing ; Leishmania (Mundinia) enriettii ; L. (M.) macropodum ; L. (M.) martiniquensis Subject RIV EE - Microbiology, Virology OECD category Microbiology R&D Projects EF16_019/0000759 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) Method of publishing Open access Institutional support BC-A - RVO:60077344 UT WOS 000500572600002 EID SCOPUS 85073109865 DOI 10.1186/s12864-019-6126-y Annotation Background: Trypanosomatids of the genus Leishmania are parasites of mammals or reptiles transmitted by bloodsucking dipterans. Many species of these flagellates cause important human diseases with clinical symptoms ranging from skin sores to life-threatening damage of visceral organs. The genus Leishmania contains four subgenera: Leishmania, Sauroleishmania, Viannia, and Mundinia. The last subgenus has been established recently and remains understudied, although Mundinia contains human-infecting species. In addition, it is interesting from the evolutionary viewpoint, representing the earliest branch within the genus and possibly with a different type of vector. Here we analyzed the genomes of L. (M.) martiniquensis, L. (M.) enriettii and L. (M.) macropodum to better understand the biology and evolution of these parasites. Workplace Biology Centre (since 2006) Contact Dana Hypšová, eje@eje.cz, Tel.: 387 775 214 Year of Publishing 2020 Electronic address https://bmcgenomics.biomedcentral.com/track/pdf/10.1186/s12864-019-6126-y
Number of the records: 1