Number of the records: 1
Epoxy-based gelcasting of machinable hydroxyapatite foams for medical applications
- 1.
SYSNO ASEP 0491306 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Epoxy-based gelcasting of machinable hydroxyapatite foams for medical applications Author(s) Štastný, P. (CZ)
Chlup, Zdeněk (UFM-A) RID, ORCID
Kalasova, D. (CZ)
Zikmund, T. (CZ)
Kaiser, J. (CZ)
Trunec, M. (CZ)Number of authors 6 Source Title Journal of the American Ceramic Society. - : Wiley - ISSN 0002-7820
Roč. 101, č. 8 (2018), s. 3317-3327Number of pages 11 s. Language eng - English Country US - United States Keywords tissue engineering applications ; in-vivo ; scaffolds ; bioceramics ; ceramics ; optimization ; regeneration ; constructs ; challenges ; kinetics ; foams ; gelcasting ; hydroxyapatite ; mills ; milling ; scaffold Subject RIV JH - Ceramics, Fire-Resistant Materials and Glass OECD category Ceramics Institutional support UFM-A - RVO:68081723 UT WOS 000434278100010 EID SCOPUS 85043510687 DOI 10.1111/jace.15523 Annotation Machinable hydroxyapatite foams for subtractive manufacturing of customized bone scaffolds have been developed. The foams were prepared by direct foaming of water-based hydroxyapatite suspension with dissolved epoxy resin. The foams were consolidated by gelation of the epoxy-based suspension in air atmosphere. The effect of processing conditions on the foam structure was investigated. The foams had a cellular-like structure with interconnected pores. The sintered foam with 78% open porosity, the most frequent pore size 430m, and the most frequent interconnecting pore window size 150m, has been chosen as the foam with the optimal structure from the viewpoint of an application in bone regeneration. The compressive strength of this sintered foam reached 3.3MPa. The machinability of the optimal foam was investigated using computer numerical controlled (CNC) milling of a test pattern. The milling tests were carried out with the foam at different processing stages and after impregnation with paraffin wax. The best milling result was obtained for a dried foam impregnated with paraffin. The applicability of the whole processing chain was demonstrated and a customized scaffold was manufactured. Workplace Institute of Physics of Materials Contact Yvonna Šrámková, sramkova@ipm.cz, Tel.: 532 290 485 Year of Publishing 2019
Number of the records: 1